This first-of-its-kind volume offers a clear and comprehensive guide to the design of non-active site-directed enzyme inhibitors, with a particular focus on allosteric modulation. Weiping Zheng distils a wide range of concepts into practical strategies that can be readily applied to diverse enzymatic systems across important physiological and pathological processes. Emphasising both effectiveness and simplicity, the book demonstrates how these approaches can reliably yield promising inhibitors for a variety of enzyme classes and therapeutic areas.

Bridging theory and application, this accessible resource is ideal for researchers seeking efficient design methodologies, while also serving as a valuable teaching text for upper-level undergraduates and early-stage graduate students. It provides readers with the tools and insight needed to advance inhibitor discovery and deepen understanding of enzyme regulation.