The history of medicine and psychiatry has witnessed many times the untoward consequences of medicine's profound professional ignorance without recognizing our error until generations later. Whether through the bloodletting of leeches, the prophylactic removal of every large intestine in the community in the hope of treating depression produced by occult sources of infection, or to the more recent ice pick rampages of thousands of frontal lobe scramblings (including the hapless Rose Kennedy) on the part of Doctor Walter Freeman as he travelled the country in his "lobotomobile" ice picking brains at every stop with the joy of an ice cream salesman.
But these people - for all the primitive harm that they produced - were actually trying to help these patients, despite the profound suffering that was the actual product of their dysfunctional medical treatments. This is in direct contrast to modern psychiatry that knows and understands the simple science of statistics and the results of comparing ketamine to all or any of psychiatrists SSRI's or SNRI's.