This book comprises a selection of articles from the 13th World Conference on Information Systems and Technologies (WorldCIST'25), held from April 15 to 17, 2025, at the Federal University of Santa Catarina, Florianópolis, Brazil.

WorldCIST is a global forum for researchers and practitioners to present and discuss recent results and innovations, current trends, professional experiences, and the challenges of modern research in Information Systems and Technologies, along with their technological developments and applications.

The main and distinctive topics covered include:

A) Information and Knowledge Management

B) Organizational Models and Information Systems

C) Software and Systems Modeling

D) Software Systems, Architectures, Applications, and Tools

E) Multimedia Systems and Applications

F) Computer Networks, Mobility, and Pervasive Systems

G) Intelligent and Decision Support Systems

H) Big Data Analytics and Applications

I) Human-Computer Interaction

J) Ethics, Computers, and Security

K) Health Informatics

L) Information Technologies in Education

M) Information Technologies in Radiocommunications

N) Technologies for Biomedical Applications

The primary target audience for this book is postgraduate students and researchers in the field of Information Systems and Technologies. The secondary audience includes undergraduate students and professionals in the same field.