This book investigates current debates shaping Higher Education development as a subsystem and higher education (HE) as a field of study in Africa. It applies meta-analysis, literature review methodologies and the lens of decolonization theories to examine both studies and key reforms characterizing the continent. The book unpacks how these remarkable and unintended transformations of universities that shape Africa can be comprehended by researching national, regional, and continental arrangements of universities and systems in order to see how all these categories either dialogue or intersect.