Leaving the fast-paced life of Kirkwood Medical Center for what they hoped would be a quieter one to raise their family, Jay Barlow, his wife, Debbie, and their two young children settle in the small, bucolic community of Esbenshade.

But the ideal life they had envisioned together turns upside down when Jay, now a paramedic, begins aiding more and more patients suffering and dying from the same condition, with no logical cause or reason. He becomes determined to find an answer with the help of his partner, colleagues, and friends.

But as his search begins to challenge his marriage and his relationship with his partner, Sam, his resolve leads him to the discovery of a far darker and deadlier threat to his adopted community and his family than any of them had feared possible.

Inspired by a true story.