Homeless and shy teen Peggy Dillan is on the run from a secret past. After daring to save a stray dog from a tormenting gang, she finds herself running right into the Farroway Animal Shelter and into something unexpected. There she meets an eccentric group of misfits in charge of the abused and neglected animals: no-nonsense, allergy-ridden Betty; cantankerous cat lady Clara; caring animal cop Joe; and Terry-the optimistic, patient, and diplomatic warden.

Enlisted into their ranks, Peggy learns to navigate the run-down, problem-ridden shelter while searching for a way to save the stray dog, Lucky, from his abusive owner. As Peggy struggles to help save the sinking shelter, she learns it's possible to change the world "one corner at a time" with courage and conviction.